Hotels in South San Francisco

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Popular hotels in South San Francisco

Discover well-known properties in South San Francisco that are favoured by visitors more than others. There are 114 hotels in South San Francisco and price data was last updated on 18 August 2025. The average price for a hotel in South San Francisco is C$ 166/night.
These hotels are among the most popular properties in the South San Francisco area. Users can use the filters present to refine their search even further.
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300 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.195% CA Tourism Assessment Fees and 0.75% San Mateo TMD Assessment Fees The Hampton Inn South San Francisco-Airport hotel in California is ideally located just 1.5 miles north of the airport off Grand Avenue/South San Francisco off Highway 101. The hotel offers courtesy transportation to and from the airport. Transportation to our BART station is also available. The hotel is 9 miles away from the New Golden State Warriors Chase Center and 10 miles away from the Oracle Park, San Francisco's Giants home. Warm to our California hospitality in one of our 100 guest rooms with comfortable queen or king beds. Our spacious and attractive hotel rooms include all the amenities you expect including our large, comfortable workspaces. Our affordable rates are designed to make your stay a wonderful experience from the moment you check in. From communications to accommodations, you will find our amenities the perfect companion for the business or leisure traveler. While at the Hampton Inn San Francisco-Airport hotel, get started each morning with our hot complimentary breakfast buffet that is served from 6:00 am - 10:00 am everyday. Or, if you have early check-out, get one of our On The Run breakfast! Everything you want in a quality hotel for a fraction of what you would expect to pay. Whether a room for yourself, or our value saving packages: Park, Stay and Go, Shop and Drop, City Tour, Wine Tour, Movie On Us or a conference setting for your group, our professional staff is eager to assist you with planning. Our San Francisco, California hotel received the Top 10% Circle of Excellence Award two years in a row and were also a winner in Product and Service. We love having you here at the Hampton Inn San Francisco-Airport hotel in California!
Free Wi-Fi
Airport shuttle
8.2
Excellent
727 reviews
Location
0.6 km from city centre
C$ 196
250 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: San Mateo County Tourism Assessment & California Tourism Assessment The Embassy Suites by Hilton San Francisco Airport Oyster Point is located in South San Francisco, just three miles north of San Francisco International Airport and 10 miles south of downtown San Francisco. Enjoy spacious accommodations in this all-suite hotel that includes a free made to order breakfast. In addition to a modern exercise facility, we offer a relaxing heated indoor pool. We also offer complimentary drinks and snacks at our Evening Reception*. Relax in our tropical atrium and experience our on-site restaurant Two-Fifty. Free WiFi for Hilton Honors members! *Service of alcohol subject to state and local laws. Must be of legal drinking age. *The guaranteed credit card will be authorized for $50, one day prior to arrival.
Pool
8.1
Excellent
1143 reviews
Location
0.6 km from city centre
C$ 253
1333 Veterans Boulevard, South San Francisco, CA, United States
This design-driven AC Hotel on the San Francisco Bay is all about modern architecture with wonderful waterfront views. Guestrooms feature sleek furnishings and the most comfortable bed you’ll sleep in besides your own. Free WiFi combines with ample amenities including an indoor pool, fitness center, flexible meeting space, and media salons. Our AC Kitchen serves up a European-inspired breakfast, while lunch and dinner in the AC Lounge are flavored with Spanish flair. Karl the Fog cocktails highlight a bar menu focused on tapas. Located in the Cove at Oyster Point, our Bay Area hotel is minutes from SFO Airport; Caltrain and the San Francisco Bay Ferry are less than a mile. Proximity to a hub of biotech companies makes it ideal for business travelers; this airport hotel is adjacent to the San Francisco Bay Trail – with convenient access to Pier 39, The Embarcadero, and Golden Gate Bridge - it’s for leisure travelers, too.
Pool
Free Wi-Fi
8.5
Excellent
564 reviews
Location
1.5 km from city centre
C$ 245
550 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.75% San Mateo TBID Assessment Fees. Right off US-101 in the birthplace of Biotechnology, Home2 Suites by Hilton San Francisco Airport North provides a comfortable stay during your business trip or vacation. Walk to the Genentech campus, or take our complimentary shuttle to and from San Francisco International Airport (SFO), just two miles away. Our hotel is also close to South San Francisco dining and shopping, as well as BART and Caltrain stations. Rest well in our contemporary, spacious suites, offering a living area, in-suite kitchen and free WiFi. A full-size refrigerator, dishwasher, cooktop and dishes make preparing meals easy. Move the furniture to suit your needs, and feel free to bring your pet along on your trip. Fuel your day with free breakfast favorites such as fresh fruit, oatmeal, eggs, cereal and more, as well as hot coffee and tea available 24-hours. If you need a snack, or forgot your toothbrush, visit out Home2 MKT anytime. Business travelers will appreciate our spacious meeting room for up to 55 people, as well as our business services area with free wireless printing. Keep up with your workout routine and run a load of laundry in our Spin2 Cycle facility.
Free Wi-Fi
8.6
Excellent
570 reviews
Location
0.8 km from city centre
C$ 231
670 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.195% CA Tourism Assessment and.75% San Francisco Peninsula Tourism Marketing District. The Hilton Garden Inn San Francisco Airport North hotel is located in California's South San Francisco, an area that many Biotech Companies call home. Our neighbors include Genentech, SAP, Amgen, Rigel and Prothena Pharmaceuticals. The Hilton Garden Inn San Francisco Airport North hotel is close to the San Francisco International Airport. While you are here, enjoy the comforts of our spacious guest rooms, including Garden Sleep System bed, complimentary WiFi and hospitality center equipped with microwave, refrigerator and coffeemaker. Treat yourself to a meal at The Garden Grille and Bar, order rooms service, or grab a snack at our 24 hour Pavilion Pantry. At Hilton Garden Inn San Francisco Airport North hotel you are close to top local attractions with easy access to Highway 101, eight miles from downtown San Francisco, one mile from Cow Palace and Oyster Point Marina, ten miles from Moscone Center, Union Square, Fisherman's Wharf, ATT Park and only eight miles from many other San Francisco attractions.
Free Wi-Fi
8.3
Excellent
693 reviews
Location
0.9 km from city centre
C$ 191
121 East Grand Avenue, South San Francisco, CA, United States
Conveniently located off Highway 101, the Comfort Inn and Suites San Francisco Airport North in South San Francisco, CA offers easy access to the San Francisco International Airport. With the City to the north and Silicon Valley to the south, our hotel serves as headquarters for a great stay. All rooms have king beds and queen-sized sofa sleepers, refrigerators, microwaves, coffee makers, irons and ironing boards, hair dryers, and TVs. Get going with a complimentary weekday newspaper and free hot breakfast that includes healthy options like yogurt and fresh fruit. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.
Free Wi-Fi
7.1
Good
1618 reviews
Location
0.3 km from city centre
C$ 178
690 Gateway Boulevard, South San Francisco, CA, United States
Perfectly situated in the heart of the Gateway and the areas thriving biotechnology industry, our South San Francisco hotel with suites is just minutes away from some of biotechs biggest names, as well as iconic sights as Fishermans Wharf, Union Square, China Town, and the Golden Gate Bridge.
Free Wi-Fi
Airport shuttle
6.8
Good
622 reviews
Location
1.0 km from city centre
C$ 183
264 South Airport Boulevard, South San Francisco, CA, United States
Elevate your trip when you stay at Four Points by Sheraton Hotel and Suites San Francisco Airport. Our contemporary San Francisco Airport hotel is just one mile from San Francisco International Airport and nine miles from the historic Bay in San Francisco, CA. Discover nearby top attractions like Coit Tower, Cow Palace Arena & Event Center, Oracle Park, Fisherman's Wharf, and Ghirardelli Square. Business travelers appreciate the location of our pet-friendly hotel in South San Francisco Airport near biotechnology companies and other corporations. After a day of working or sightseeing, get in a quick workout at our on-site fitness center and then retreat to one of our renovated hotel suites with luxury bedding, high-speed Wi-Fi, and a flat-panel TV. Whether you're traveling with family, friends, or colleagues, save on your stay when you book a block of hotel rooms. Find everything you need to travel the way you like at Four Points by Sheraton Hotel and Suites San Francisco Airport.
Free Wi-Fi
7.0
Good
280 reviews
Location
0.8 km from city centre
C$ 178
1350 Veterans Boulevard, South San Francisco, CA, United States
Hotel with free breakfast, near San Francisco Bay This smoke-free hotel features an outdoor pool, a fitness center, and a snack bar/deli. Free buffet breakfast, free WiFi in public areas, and a free airport shuttle are also provided. Other amenities include a hot tub, coffee/tea in a common area, and a business center. Weekly housekeeping is available. Sonesta ES Suites San Francisco Airport Oyster Point Waterfront offers 152 accommodations with coffee/tea makers and hair dryers. Accommodations offer separate sitting areas. Pillowtop beds feature Frette Italian sheets and premium bedding. A pillow menu is available. Flat-screen televisions come with premium cable channels and pay movies. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and dishwashers. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Change of towels and change of bedsheets can be requested. Housekeeping is provided weekly. An outdoor pool and a hot tub are on site. Other recreational amenities include a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Free Wi-Fi
7.8
Good
410 reviews
Location
1.8 km from city centre
C$ 209
760 El Camino Real, South San Francisco, CA, United States
Motel in South San Francisco with free parking Along with a 24-hour front desk, this smoke-free motel has free self parking and free WiFi in public areas. Other amenities include a vending machine. Americana Inn offers 17 air-conditioned accommodations with coffee/tea makers and hair dryers. Flat-screen televisions are featured in guestrooms. Refrigerators and microwaves are provided. Bathrooms include shower/tub combinations. This South San Francisco motel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.
Free Wi-Fi
Parking
7.8
Good
332 reviews
Location
2.1 km from city centre
C$ 200

Travel insights for hotels in South San Francisco

Use these up-to-date, data-driven insights about booking a hotel in South San Francisco including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in South San Francisco?

The cheapest month to book a hotel in South San Francisco is October (C$ 91). Conversely, the most expensive month to stay in South San Francisco is February (C$ 349).

What is the cheapest day to stay in a hotel in South San Francisco?

The cheapest day to stay in South San Francisco is Friday (C$ 111). On the other hand, travelers can expect to pay the most on Monday, when the average nightly price is C$ 375.

How much is a hotel in South San Francisco tonight?

Users have found prices for hotels in South San Francisco tonight starting as low as C$ 127, rising to an average cost of C$ 211, based on searches in the last 72 hours. Prices start from C$ 232 for a 4-star hotel in South San Francisco for tonight.

How much is a South San Francisco hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in South San Francisco this weekend for as little as C$ 124/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as C$ 136/night. For a 4-star hotel in South San Francisco, the cheapest rate recently found was C$ 221/night for this weekend.

Cheapest hotels in South San Francisco, California

Discover affordable stays in South San Francisco that provide a quality experience without breaking the bank. Hotels in South San Francisco can be found for as low as C$ 95 per night. There is currently one property in South San Francisco that can be booked for this price. Travelodge by Wyndham San Francisco Airport North is one of the hotels that can be booked for the lowest price in South San Francisco. Price data was last updated on 18 August 2025
At the moment, these hotels offer the lowest nightly rate out of those we've come across in South San Francisco. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
326 South Airport Boulevard, South San Francisco, CA, United States
1.1 km from city centre
Free Wi-Fi
C$ 95
Avg. per night
245 South Airport Boulevard, South San Francisco, CA, United States
0.8 km from city centre
Free Wi-Fi
Parking
Airport shuttle
Air Conditioning
C$ 113
Avg. per night
111 Mitchell Avenue, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
C$ 127
Avg. per night
721 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
Airport shuttle
C$ 139
Avg. per night
701 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
Parking
C$ 142
Avg. per night
1113 Airport Boulevard, South San Francisco, CA, United States
1.2 km from city centre
Free Wi-Fi
C$ 144
Avg. per night
800 El Camino Real, South San Francisco, CA, United States
2.1 km from city centre
Free Wi-Fi
Parking
C$ 163
Avg. per night
920 El Camino Real, South San Francisco, CA, United States
2.2 km from city centre
Free Wi-Fi
Parking
C$ 167
Avg. per night
380 South Airport Boulevard, South San Francisco, CA, United States
1.3 km from city centre
Free Wi-Fi
C$ 168
Avg. per night
120 Hickey Boulevard, South San Francisco, CA, United States
4.2 km from city centre
Free Wi-Fi
Parking
C$ 169
Avg. per night
410 South Airport Boulevard, South San Francisco, CA, United States
1.4 km from city centre
Free Wi-Fi
Airport shuttle
C$ 170
Avg. per night
751 Airport Boulevard, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
Air Conditioning
C$ 171
Avg. per night
100 Hickey Boulevard, South San Francisco, CA, United States
4.1 km from city centre
Free Wi-Fi
Air Conditioning
C$ 177
Avg. per night
20 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
C$ 177
Avg. per night
1300 Veterans Boulevard, South San Francisco, CA, United States
1.7 km from city centre
Free Wi-Fi
C$ 177
Avg. per night

Hotel prices in South San Francisco

Get a sense of the average price and most popular properties to stay in South San Francisco to help you budget for your trip accordingly. Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” badge are the most popular hotels in South San Francisco at attractive prices. Price data was last updated on 18 August 2025.
An overview of the average price of hotels by hotel class in the South San Francisco. For added insight, we've also noted the most popular and best value hotels within each hotel class.
3 stars
300 Gateway Boulevard, South San Francisco, CA, United States
C$ 196
380 South Airport Boulevard, South San Francisco, CA, United States
C$ 168
111 Mitchell Avenue, South San Francisco, CA, United States
C$ 127
2 stars and under
701 Airport Boulevard, South San Francisco, CA, United States
C$ 142
920 El Camino Real, South San Francisco, CA, United States
C$ 167
326 South Airport Boulevard, South San Francisco, CA, United States
C$ 95

Other accommodations in South San Francisco

Find the perfect hostel, theme hotel, or vacation rental for your stay in South San Francisco. There are 114 hotels in South San Francisco and price data was last updated on 18 August 2025. The average price for a stay in South San Francisco is C$ 166/night.
410 South Airport Boulevard, South San Francisco, CA, United States
1.4 km from city centre
Free Wi-Fi
Airport shuttle
C$ 170
Avg. per night
670 Gateway Boulevard, South San Francisco, CA, United States
0.9 km from city centre
Free Wi-Fi
C$ 191
Avg. per night
1300 Veterans Boulevard, South San Francisco, CA, United States
1.7 km from city centre
Free Wi-Fi
C$ 177
Avg. per night
920 El Camino Real, South San Francisco, CA, United States
2.2 km from city centre
Free Wi-Fi
Parking
C$ 167
Avg. per night
751 Airport Boulevard, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
Air Conditioning
C$ 171
Avg. per night

Where to stay in South San Francisco

Explore different neighbourhoods and areas within South San Francisco to find the perfect location for your stay. Map data was last updated on 18 August 2025.
Whether you're visiting South San Francisco for leisure or business, utilize the map to find hotels close to your ideal location. Clicking a property's name will unlock more information and allow you to book that particular hotel.

About South San Francisco

Often referred to as “South City”, this Bay Area city lies in a valley just to the north of the San Francisco International Airport. It boasts impressive views across the bay, with hills that shield it from the fog San Francisco is renowned for and is noted for the large white letters on Sign Hill which have proudly declared it as “South San Francisco, The Industrial City” since 1923.

Grand Avenue is the heart of South San Francisco, lined with buildings dating back to the city’s earliest days including the neo-colonial Georgian City Hall, designed after Philadelphia's Independence Hall, together with the Carnegie Library and the Metropolitan Hotel, built by the Meat Packers Consortium in 1912. Orange Memorial Park is one of the city’s most beautiful green spaces, with picnic grounds, a sculpture garden, children’s playground and Saturday farmer’s market, while its 28-metre tall Wind Harp sculpture stands as the largest aeolian harp in the world. Undoubtedly South San Francisco’s most popular attraction is Sign Hill, with the heritage-listed landmark visible across the peninsula. It’s been recognised as an outstanding example of 20th century “civic boosterism” and the role that local industries have played in not only the regional economy but also the war effort. Today this iconic sign is surrounded by a city park with numerous hiking trails to explore and offers fantastic panoramas across the Bay Area.

South San Francisco is connected to the city of San Francisco, the SFO international airport and the East Bay along the rapid transit system, with free shuttle services between the downtown area and the main BART station. There are also ferry services between the Oyster Point Marina and both Oakland and Alameda in the East Bay area during weekday commuter hours.

The area that is now South San Francisco was originally part of an early 19th century Mexican land grant, before being conceived as an industrial suburb towards the end of the century by a group of influential meat packing companies. Other industries soon moved into the area, including paint manufacturers, lumber and steel yards, brick and pottery works, firmly establishing the city as an industrial hub dubbed “the smokestack capital of the Peninsula”.

Facts about staying in South San Francisco

Find useful tips and insights about staying in South San Francisco to help you make the most of your experience. FAQs were last updated on 18 August 2025.
  • What are the best hotels in South San Francisco?

    South San Francisco is home to many highly-rated hotels, one of which is Comfort Inn & Suites San Francisco Airport North, which has a current rating of 7.1. For other potential stays, consider Best Western Plus Grosvenor Airport Hotel and Embassy Suites by Hilton San Francisco Airport Oyster Point, which can also be great places to stay in South San Francisco.

  • What is a good hotel near Embassy Suites by Hilton San Francisco Airport?

    Best Western Plus Grosvenor Airport Hotel is a hotel near Embassy Suites by Hilton San Francisco Airport that is popular with HotelsCombined users, scoring 7.8 across 3,244 reviews.

  • What is a good hotel in South San Francisco near Sign Hill Park?

    Embassy Suites by Hilton San Francisco Airport Oyster Point is rated 8.1 from 1,143 reviews and is close to Sign Hill Park.

  • Is there a good hotel near South San Francisco Convention Center?

    If you’re looking for good hotels near South San Francisco Convention Center, consider Best Western Plus Grosvenor Airport Hotel (rated 7.8 over 3,244 reviews).

  • Are there any hotels in South San Francisco close to San Francisco?

    The closest hotel to San Francisco is Hotel Nova SFO by Fairbridge, which is located 1.4 km away from the city center.

  • What are some other cities to stay in when visiting California?

    In addition to South San Francisco, travellers opt to visit Los Angeles when visiting California. San Francisco is also a popular choice to visit.

  • How many hotels are there in South San Francisco?

    In total, there are 114 hotels to choose from in South San Francisco, compared to 118,313 properties in California.

  • What are the most popular landmarks to visit in South San Francisco?

    The most popular landmarks in South San Francisco are Embassy Suites by Hilton San Francisco Airport (in South San Francisco), Sign Hill Park (in South San Francisco), and South San Francisco Convention Center (in South San Francisco) according to our user data. If you plan to visit any of these, we recommend finding a hotel nearby to cut down on travel time.

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